Leucine And Ketosis: Friends or Foes

Thursday, June 24, 2021

Leucine is valued for its incredible ability to boost muscle mass and improve athletic performance. Not only that, but it can also prevent muscle deterioration. It also helps you get into and maintain the ketosis phase in a ketogenic diet! Let’s find out how.

BCAA – Muscle building block

BCAA is a very well-known and popular term in the sports and fitness world. BCAAs are branched chain amino acids that are made up of three essential amino acids leucine, isoleucine and valine, which comprises around one-third of our body’s muscle protein. Depending on the way the body metabolizes and utilizes them, they can also be classified as glucogenic, ketogenic or glucogenic-ketogenic.

Glucogenic amino acids make glucose for fuel, whereas ketogenic amino acids convert into soluble compounds called ketone bodies via a process called ketogenesis. Leucine is a ketogenic amino acid whereas Valine is glucogenic amino acids and Isoleucine is both in nature.

Leucine - is one of the ketogenic amino acids among two (other one being Lysine), meaning they are able to be converted into ketone bodies by degrading directly into acetyl-CoA. It also contributes to regulation of blood-sugar levels; growth and repair of muscle and bone tissue; growth hormone production; and wound healing. It also prevents breakdown of muscle proteins after trauma or severe stress.

Isoleucine and Valine - are glucogenic Amino acid means, it can be converted into glucose through gluconeogenesis.

Glucogenic amino acids make glucose for fuel, whereas ketogenic amino acids convert into soluble compounds called ketone bodies via a process called ketogenesis. Leucine is a ketogenic amino acid whereas Valine is glucogenic amino acids and Isoleucine is both in nature.

What Makes Leucine Special!

- Ketogenic Amino Acid:

Being a Ketogenic Amino Acid, Leucine forms a type of ketone body known as acetoacetate, by first yielding the intermediary compound acetyl-CoA.

These ketone bodies, body uses as fuel source when glucose is unavailable, in conditions like fasting, starvation or deliberately eliminating carbs from your lifestyle, most popularly known as Ketogenic or Keto diet. Thus, it increases plasma concentrations of ketone bodies and helps you remain in ketosis.

Leucine - is one of the ketogenic amino acids among two (another one is Lysine), meaning they are able to be converted into ketone bodies by degrading directly into acetyl-CoA.

- King of Muscle synthesis:

Although together BCAAs play numerous key roles in your body but among all 3 BCAAs, Leucine plays a prime role in muscle protein synthesis. Here are some of their key benefits:

  1. Leucine helps to promote protein synthesis and is also essential for providing energy for your muscles to use.
  2. It has a regulatory role in the chemical reactions involved in the weight loss effects associated with high-protein diets.

- King of Muscle synthesis:

Although together BCAAs play numerous key roles in your body but among all 3 BCAAs, Leucine plays a prime role in muscle protein synthesis. Here are some of their key benefits:

  1. Leucine helps to promote protein synthesis and is also essential for providing energy for your muscles to use.
  2. It has a regulatory role in the chemical reactions involved in the weight loss effects associated with high-protein diets.

- Isoleucine and Valine May Kick You Out of Ketosis but NOT Leucine:

A ketogenic diet goes relatively moderate on protein and very high in fat, whereas carbs are limited to up to 30-50gm/day. Ketone bodies have a protein-preserving effect, so even moderate dietary protein is sufficient enough to preserve muscle. However, there is no doubt that BCAAs play a very important role in muscle building and maintenance. While you are on a keto diet, you can protect your muscles by sipping fluids high in BCAAs as intra and post workout.

But, be aware that drinking too much BCAA-enriched fluids or drinking them too frequently can unintentionally increase the insulin levels, as isoleucine and valine being glucogenic amino acids get converted into glucose, which may throw you out of ketosis.

Drinking too much BCAA-enriched fluids or drinking them too frequently can unintentionally increase the insulin levels, as isoleucine and valine being glucogenic amino acids get converted into glucose, which may throw you out of ketosis.

Muscle Building on Keto – Leucine is the Key

Leucine on the other hand, is a great anabolic support as it promotes muscle growth and reduce muscle loss while on a high fat, moderate protein and low carb diet.

As you can see, there are important connections between certain chain amino acids and the process known as ketosis which is at the heart of the low-carb lifestyle. What if there was a supplement you could take that would help you give those ketogenic amino acid functions a boost? If there was, you would be able to achieve greater efficiency in your fat burning efforts, shorter recovery after workouts and more effective repair of muscle tissue. Then you could truly realize the latent potential of the low-carb diet and help transform your body and mind in a harmonious, well-oiled machine.

L-leucine supplements are popular in the bodybuilding and athletic community (Sports Nutrition) because leucine is a great anabolic support as it promotes muscle growth and reduce muscle loss while on a high fat, moderate protein and low carb diet

WE SAY

PROCEL BETA LEUCINE is a broad-spectrum supplement that’s designed to help those on the lifestyle, recover more effectively after workouts, build lean, hard muscle and improve their body to metabolize fat into energy quicker and more effectively.

It provides an array of ingredients designed to optimize the production of ketone bodies and promote more vigorous fat burning.